A Duke University study of major depressive disorder found that exercise was as effective as an antidepressant (Zoloft) in treating adults (N=202) after four-months. The September issue of the Journal of Psychosomatic Medicine reports that patients who were randomly assigned to two groups using aerobic exercise (at home or in a supervised group setting) scored about the same as those taking antidepressants on the Hamilton Rating Depression Scale, a standard evaluation. Both did better than the placebo group. Depression is the fourth leading cause of disability and by 2020 it is expected to be second following heart disease.

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