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The selection of articles reaching print might overstate the benefit of antidepressants, according to a study published in the New England Journal of Medicine. The authors examined clinical studies of 12 antidepressants, involving 12,564 patients, registered with the FDA and concluded that most published studies showed positive results. But one-third of the clinical studies showing that the agent was no better than a placebo were not published. Selective reporting of clinical trials which emphasize only the benefits, “may have adverse consequences for researchers, study participants, health care professionals, and patients,”
the authors said.

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