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St. John's wort and depression
St.john'swort(istock).jpegiStock
For many years the plant St. John's wort was considered a folk remedy to treat depression. Now an analysis of 29 clinical trials (n=5489) concludes Hypericum perforatum L. performed better than a placebo and as well as standard antidepressants and with fewer side effects. The Cochrane Library report sounded a cautionary note because numerous forms and extractions of Hypericum perforatum L. may not be identical to those in the study. Better study outcomes were also apparent in German-speaking countries where St. John's wort has been part of the standard treatment for depression, anxiety and sleep disorders.

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