Allegations that AstraZeneca failed to warn patients that its drug Seroquel contributed to weight gain and diabetes came to light yesterday when documents were opened as part of a lawsuit over the billion dollar anti-psychotic drug. Instructions to divert direct questions about side effects advised the sales force to "neutralize" concerns about this despite knowing it's own doctor pointed to "reasonable evidence" about impaired glucose regulation." Court documents also reveal off-label use, and the vetting of negative trials. The case has consolidated about 9,000 plaintiffs and is being heard in US District Court in Florida.
Many of the allegations echo charges in lawsuits involving Zyprexa and the marketing practices of Bristol-Myers Squibb and Abilify.
The company also learned that the FDA wanted more information before approving an application for a long-acting, slow release drug.
I was given three hundred mg of seroquel and was unable to get out of bed to go to the restroom as I wold fall down. There was no sleep as the drug put me on the edge of non responsive sleep disorder I could not eat as I was too week and I tried to go driving to ick up one one night and was hallucinating behind the wheel as I drove. I quit and the week befor the doctor told me I had diabetes 11 and pancreatis. I am very shot up and am suing.
Posted by Gary M Caldwell | October 30, 2009 9:02 PMMost of the medication that I have been on has caused weight gain!!! Seroquel is no different!!! I take my meds and go to bed, because I fell down the steps and retore my rotator cuff!! It does make me sleepy, which is good considering I have insomnia!!
All my medication comes along with all the side-effects listed. And I have used the computer to look-up medication.
Posted by Anne | February 27, 2010 7:48 PM
My doctor told me not to worry about Seroquel even though I was gaining a lot of weight. I cut down my dose because she had me on two hundred mg I thought is was unsafe because she halfway warned me by saying she has patients on higher doses with no problems. This is terrible and not to know is appalling. Companies are getting away with murder, the consumer should be told about the risk in full detail to make their own decisions about the medicine is prescribed. It's as if mental health patients do not have a clue about their own health. Doctor stigma.
Posted by Scepter | March 10, 2009 6:35 PM